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CMSC INforMS: Multiple sclerosis risk higher in children and adolescents with type 1 diabetes: Study

Thursday, July 14, 2016  
Posted by: Elizabeth Porco
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Multiple sclerosis (MS) risk is higher in children and adolescents with type 1 diabetes, according to research. Susanne Bechtold, M.D., a pediatric endocrinologist and diabetologist at Ludwig Maximilians University in Munich, Germany, wrote, “Type 1 diabetes and [multiple sclerosis] are organ-specific inflammatory diseases, which result from an autoimmune attack against either pancreatic β-cells or central nervous system; a combined appearance has been described repeatedly. We hypothesize that antibodies (namely, diabetes-specific antibody, celiac disease- or thyroid-specific antibodies), BMI, immigrant background, or month of birth might have a major impact on the coincidence of type 1 diabetes and MS.”

The researchers used a database to estimate the relative risk of multiple sclerosis in children and adolescents with diabetes. The analysis demonstrated the estimated relative risk of multiple sclerosis in type 1 diabetic youth to be 3.35 to 4.79 percent for the German reference data and 2.01 to 11.39 percent for the mid-European reference data.

Factors contributing to the risk of multiple sclerosis included immigration status and thyroid antibodies – primarily among males. Type 1 diabetics who developed multiple sclerosis were more likely to be born in the spring and summer months, with highest incidences among those born in June and July, and the lowest rates among those born in April.

The authors wrote, “The risk of autoimmune diseases might be linked to month of birth through seasonal maternal vitamin D deficiencies. Lower UV exposure might predict for a higher autoimmune susceptibility, explaining the co-occurrence of several autoimmune diseases in one person.”

“The present cohort study demonstrates a higher risk of co-occurrence of MS in a pediatric and adolescent diabetes population. We suggest that environmental factors modulate the individual’s risk for the co-occurrence of both diseases,” the authors concluded.

Healthy lifestyle changes for people with multiple sclerosis

Multiple sclerosis can lead to other health complications, so healthy lifestyle changes are important not only for preventing other ailments, but also for improving multiple sclerosis symptoms and flare-ups. Here is a list of some simple healthy lifestyle changes multiple sclerosis patients should embrace in their daily lives.

  • Don’t smoke
  • Exercise regularly
  • Eat a healthy diet and avoid any nutritional deficiencies
  • Reduce stress
  • Reduce your risk of infection like colds and flu
  • Get plenty of rest
  • Stay cool
  • Get support and develop coping mechanisms – maintain daily activities as much as possible, stay connected with friends and family, continue to pursue favorite hobbies, get in touch with a support group if necessary, discuss your feelings and concerns surrounding multiple sclerosis with your doctor

By implementing these healthy lifestyle changes into your daily life, you can better manage your multiple sclerosis.

By Mohan Garikiparithi

Bel Marra Health

CMSC Disclaimer 
The industry news information and articles are for informational purposes only, and are not intended to represent any trends, partnerships, commitments, or research of the Consortium of MS Centers or any of it's members in any way whatsoever, nor should any party be libel in any way to the reader or to any other person, firm or corporation reading this industry news section. Although the CMSC site includes links providing direct access to other Internet sites, CMSC takes no responsibility for the content or information contained on those other sites, and does not exert any editorial or other control over those other sites. CMSC is providing information and services on the Internet as a benefit and service in furtherance of CMSC's nonprofit and tax-exempt status. CMSC makes no representations about the suitability of this information and these services for any purpose.


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