The AAN published a new guideline, Practice Guideline: Disease-modifying Therapies for Adults with Multiple Sclerosis, in Neurology® online on April 23, 2018, and in print in the April 24 issue. A press conference on the guideline was held on April 23 at the AAN Annual Meeting for national and international media.
According to the guideline, several disease-modifying therapies (DMTs) are effective in reducing the rate and risk of MS relapses and new or enlarging MRI-detected lesion formation. The question of whether to start a DMT, switch from one DMT to another, or stop a DMT depends on the benefits and risks of the medications and a personalized approach to each patient.
The guideline highlights key findings and provides guidance that clinicians will find helpful:
•Careful risk management and personalization of treatment strategy are important.
•For several DMTs, there is moderate to strong evidence supporting their use; the evidence from comparative efficacy trials is less strong.
•For some DMTs, the evidence is insufficient to determine efficacy but provides information regarding risk of adverse effects.
Read the guideline and access PDF summaries for clinicians and patients and a slide presentation set at AAN.com. For more information, email firstname.lastname@example.org or call (612) 928-6069.
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